| Description | This entry represents a domain found in cell surface hyaluronidase (also known as TMEM2) and CEMIP. This domain is similar to Pancreatic-derived factor PANDER (also known as FAM3B) [ ], and is found C-terminal to a glycine rich G8-domain. The function of the PANDER-like domain in TMEM2 is not clear.TMEM2 is a cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5kDa fragments [ ]. CEMIP is a hyaluronan binding protein involved in hyaluronan depolymerisation []. | Name | Cell surface hyaluronidase, PANDER-like domain |
| Short Name | TMEM2_PANDER-like | Type | Domain |
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