Description | The LiaRS two-component system is part of the regulatory network orchestrating the cell-envelope stress response in Bacillus subtilis. It responds to perturbations with the cell envelope, especially antibiotics that interfere with the lipid II and undecaprenol cycle, such as bacitracin or vancomycin. LiaRS-dependent regulation is strictly repressed by the membrane protein LiaF and it integrates both positive and negative feedback loops to transduce cell envelope stress signals [ , ]. This entry represents a group of cell wall-active antibiotic response proteins, including LiaF and YvqF types. | Name | Cell wall-active antibiotic response protein LiaF |
Short Name | Cell_wall_LiaF | Type | Family |