Description | This family of proteins includes members that are involved in various biological processes, including the transport and breakdown of heme, cell adhesion, spreading, and inhibition of the membrane-damaging effect of the terminal cytolytic complement pathway. Some family members bind heme and transport it to the liver for iron recovery, while others are involved in cell-to-substrate adhesion and interact with glycosaminoglycans, proteoglycans, and certain integrins. Additionally, some proteins in this family have been identified as inhibitors of proteases and play roles in boundary lubrication within articulating joints, preventing protein deposition onto cartilage from synovial fluid. | Name | Heme transport and cell adhesion protein |
Short Name | Heme_transport/Cell_adhesion | Type | Family |