Description | The protein family is involved in cell fate determination, differentiation, proliferation, and apoptotic programs through Notch signaling. Members function as receptors for ligands such as Jagged and Delta proteins, influencing various developmental processes including cardiovascular development, hematopoiesis, neurogenesis, and angiogenesis. They also play roles in maintaining stem cell populations, regulating immune system development, and contributing to tissue morphogenesis and integrity. Some members regulate adipogenesis, while others are involved in maintaining the structure and function of photoreceptor cells or the extracellular matrix. | Name | Notch Signaling and Cell Fate Determination |
Short Name | Notch_Cell-Fate_Det | Type | Family |