| Description | The T cell receptor (TCR) variable domain family is involved in antigen recognition and the immune response. TCRs are present on T lymphocytes' surfaces and recognize peptide-major histocompatibility complexes displayed by antigen-presenting cells, initiating an immune response. The variable domain of the alpha or delta chain participates in antigen binding, leading to the activation of signaling pathways essential for T cell growth, differentiation, and the adaptive immune response. The TCR repertoire is generated through V-(D)-J rearrangement and shaped by selection events to create a pool of self-restricted, non-autoaggressive T cells. | Name | T cell receptor variable domain |
| Short Name | TCR_variable_domain | Type | Family |
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