| Description | The protein family includes cell surface receptors and adhesion molecules with diverse roles in cell-cell interactions, signaling, and inflammatory responses. Members of the family mediate heterotypic and homotypic cell-cell contacts, often through interactions with specific ligands such as CD6 or laminin. They are involved in various physiological processes including T-cell activation, hematopoiesis, endothelial cell migration, and vascular tissue cohesion. Some members act as pattern recognition receptors, sensing stress signals and mediating pro-inflammatory responses through NF-kappa-B activation. They also play roles in neural development, tumor spread, and endothelial permeability. The family's involvement in pathfinding for axons and retinal ganglion cells highlights its significance in neural network formation. | Name | Cell Surface Receptors and Adhesion Molecules |
| Short Name | Surface_Rcpt/Adhesion_Mol | Type | Family |
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