DB identifier
|
AT3G57300 | Secondary Identifier
|
locus:2082608 |
| Name
|
INO80 ortholog | Brief Description | DNA helicase INO80-like protein |
| TAIR Computational Description | DNA helicase INO80-like protein;(source:Araport11) |
| TAIR Curator Summary | Encodes the Arabidopsis INO80 ortholog of the SWI/SNF ATPase family that has been shown to interact with H2A.Z and facilitates the enrichment of H2A.Z at the ends of the flowering repressor genes FLC and MAF4/5. Functions as a positive regulator of DNA homologous recombination (HR) and plays a crucial role in genome stability maintenance. In INO80 mutants, the HR frequency is reduced to 15% of that in the wild-type. Plants mutated in INO80 display a pleiotropic phenotype including smaller plant and organ size, and late flowering but are not more sensitive to genotoxic agents or less efficient at T-DNA integration. INO80 has also been shown to regulate a subset of the Arabidopsis transcriptome. |
| TAIR Short Description | INO80 ortholog |
| TAIR Aliases | ATINO80, INO80 |
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