Description | The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate [ , ].The enzymes have a wide range of functions. In plants UDP-glucose dehydrogenase, , is an important enzyme in the synthesis of hemicellulose and pectin [ ], which are the components of newly formed cell walls; while in zebrafish UDP-glucose dehydrogenase is required for cardiac valve formation []. In Xanthomonas campestris, a plant pathogen, UDP-glucose dehydrogenase is required for virulence [].This entry represents an α helical region that serves as the dimerisation interface for these enzymes [ , ]. | Name | UDP-glucose/GDP-mannose dehydrogenase, dimerisation |
Short Name | UDP-Glc/GDP-Man_DH_dimer | Type | Domain |