| Description | This entry includes inosine-5'-monophosphate dehydrogenases and guanosine 5'-monophosphate (GMP) reductase. Inosine-5'-monophosphate dehydrogenase catalyses the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth [ , ]. GMP catalyses the irreversible NADPH-dependent deamination of GMP to IMP []. | Name | Inosine-5'-monophosphate dehydrogenase |
| Short Name | IMP_DH | Type | Family |
Powered by
Have you tried our InterMine mobile apps?
and interoperation is funded by 
