Description | This entry represents gamma-aminobutyraldehyde dehydrogenase (PatD, ) involved in the second step in one of two pathways for putrescine degradation. It catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA) [, ]. It also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate []. It can also oxidize n-alkyl medium-chain aldehydes, but with a lower catalytic efficiency [, ]. | Name | Gamma-aminobutyraldehyde dehydrogenase |
Short Name | PatD | Type | Family |