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Protein : CKB11_ARATH A. thaliana

Primary Accession  ? P25859 Organism . Name  Arabidopsis thaliana
Length  309   MD5 Checksum  f24c4e9150a6719be836f2982518318b
UniProt Accession  P25859 Is UniProt Canonical  true
UniProt Name  CKB11_ARATH Is Fragment  false
Molecular Weight  35318.0 Name  Cyclin-dependent kinase B1-1
Secondary Identifier  P25859

8 Comments

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1 Genes

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1 Organism

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20 Publications

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Genomics

2 Cross References

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1 Genes

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Proteins

Curated comments from UniProt

Type Comment
developmental stage Preferentially expressed in the S and G2 phases. Expressed in actively dividing cells: root and shoot apical meristems, leaf primordia and emerging lateral root meristem. Expressed in light-grown seedlings from 1 up to 7 days after germination with a peak at 2 and 3 days. Observed in late guard mother cells (GMC), newly formed guard cells, and immature stomata, thus being expressed just before and after the symmetric division of stomatal differentiation (PubMed:20675570).
function May control G2/M (mitosis) phase progression. Plays a role in regulating seedling growth in darkness via regulation of hypocotyl cell elongation and cotyledon cell development. Plays a role in stomatal development. Required to suppress endoreduplication. Together with CDKB1-2, promotes both the last division in the stomatal cell lineage as well as the number of stomata (PubMed:20675570). In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248, PubMed:24687979).
similarity Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
tissue specificity Highly expressed in guard cells and stomatal precursor cells of cotyledons. Expressed in roots, stems, flowers and siliques.

14 Features

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0 Isoforms

11 Keywords

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7 Protein Domain Regions

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1 Sequence

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Other

0 Canonical Protein

0 Components

2 Data Sets

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2 Ec Numbers

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0 Locations