Description | Phosphoribosyl-ATP pyrophosphatase, catalyses the second step in the histidine biosynthetic pathway: 5-phosphoribosyl-ATP + H2O = 5-phosphoribosyl-AMP + PPiThe Neurospora crassa enzyme also catalyzes the reactions of histidinol dehydrogenase ( ) and phosphoribosyl-AMP cyclohydrolase ( ). This entry also includes the Bacillus subtilis Cof proteins, which catalyze the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate [ ]. | Name | Phosphoribosyl-ATP pyrophosphohydrolase-like |
Short Name | PRib-ATP_PPHydrolase-like | Type | Family |