Description | This family includes a group of proteins from bacteria and archaea, which belong to the thiamine pyrophosphate (TPP family) [ , ], such as pyruvate oxidase (POXB) from Lactobacillus plantarum which decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate []. This entry also includes a closely homologous member, pyruvate dehydrogenase [ubiquinone]PoxB from Escherichia coli, a peripheral membrane protein that catalyses the oxidative decarboxylation of the central metabolite pyruvate to CO(2) and acetate. It has pyruvate oxidase as an alternate name [ , , , , ]. | Name | Pyruvate oxidase/Pyruvate dehydrogenase [ubiquinone]-like |
Short Name | POXB-like | Type | Family |