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Protein Domain : IPR003680

Description  This entry represents a domain with a flavodoxin-like fold.Proteins with this domain include bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) . These enzymes catalyse the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species [ ]. This enzyme uses a FAD cofactor. The equation for this reaction is NAD(P)H + acceptor = NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy []. This domain is also found in acyl carrier protein phosphodiesterase . This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP [ ]. Name  Flavodoxin-like fold
Short Name  Flavodoxin_fold Type  Domain
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2 Publications

Genomics

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1 Data Sets

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