Description | This entry represents a group of dehydroascorbate reductases (DHARs), including DHAR1/2/3/4 from Arabidopsis. They act as thiol transferases but have no glutathione conjugating activity [ ]. They catalyse the glutathione (GSH)-dependent reduction of oxidized ascorbate (dehydroascorbate, DHA). As a result, DHARs regenerate a pool of reduced ascorbate and detoxify reactive oxygen species (ROS) []. Unlike most other glutathione transferases, DHARs are monomeric []. DHAR2 and DHAR4 are predicted to be cytosolic, while DHAR3 is predicted to be chloroplastic, and DHAR1 is predicted to be mitochondrial. The cytosolic DHAR is important for ozone tolerance []. | Name | Dehydroascorbate reductases DHAR1/2/3/4 |
Short Name | DHAR1/2/3/4 | Type | Family |