help  | faq  | software  | BAR

Protein Domain : IPR009757

Description  This family represents the anti-apoptotic ORF4 protein from Circovirus 2, which antagonises host cell apoptosis by interacting with host ferritin heavy chain (FHC). This protein physically binds host FHC, resulting in the reduction of FHC protein levels in host cells. The reduction of FHC concentration further inhibits the accumulation of reactive oxygen in host cells, leading to reduced apoptosis [ ]. Name  Circovirus 2, anti-apoptotic ORF4
Short Name  Circovirus2_Orf4 Type  Family
Quick Links:
 
Quick Links:
 

1 Publications

Genomics

1 Cross References

 

Other

0 Child Features

1 Data Sets

0 Parent Features

0 Protein Domain Regions