Description | NADH:ubiquinone oxidoreductase (complex I) ( ) is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) [ ]. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins [ ].This family consists of several NADH dehydrogenase [ubiquinone] 1 subunit C2 (NDUC2 or NDUFC2, also known as NADH-ubiquinone oxidoreductase subunit b14.5b) proteins. It is an accessory protein, not involved in catalysis [, ]. | Name | NADH dehydrogenase [ubiquinone] 1 subunit C2, NDUC2 |
Short Name | NDUC2 | Type | Family |