| Description | This entry represents RNA ligase 1 from animals (RLIG1), which functions as an RNA ligase in vitro [ ]. This protein catalyses ATP-dependent RNA ligation via a three-step mechanism, involving tandem auto- and RNA AMPylation. It exhibits selectivity for single-stranded RNA substrates and may not have nick-sealing activity on double-stranded DNA-RNA hybrids []. RLIG1 May play a role in maintaining RNA integrity under stress conditions, for example in response to reactive oxygen species (ROS) []. | Name | RNA ligase 1 |
| Short Name | RLIG1 | Type | Family |
Powered by
Have you tried our InterMine mobile apps?
and interoperation is funded by 
