help  | faq  | software  | BAR

Protein Domain : IPR041211

Description  This entry represents RNA ligase 1 from animals (RLIG1), which functions as an RNA ligase in vitro [ ]. This protein catalyses ATP-dependent RNA ligation via a three-step mechanism, involving tandem auto- and RNA AMPylation. It exhibits selectivity for single-stranded RNA substrates and may not have nick-sealing activity on double-stranded DNA-RNA hybrids []. RLIG1 May play a role in maintaining RNA integrity under stress conditions, for example in response to reactive oxygen species (ROS) []. Name  RNA ligase 1
Short Name  RLIG1 Type  Family
Quick Links:
 
Quick Links:
 

1 Publications

Genomics

2 Cross References

 

Other

0 Child Features

1 Data Sets

0 Parent Features

0 Protein Domain Regions