DB identifier | AT5G16850 | Secondary Identifier | locus:2148975 |
Name | telomerase reverse transcriptase | Brief Description | telomerase reverse transcriptase |
TAIR Computational Description | telomerase reverse transcriptase;(source:Araport11) |
TAIR Curator Summary | Encodes the catalytic subunit of telomerase reverse transcriptase. Involved in telomere homeostasis. Homozygous double mutants with ATR show gross morphological defects over a period of generations. TERT shows Class II telomerase activity in vitro, indicating that it can initiate de novo telomerase synthesis on non-telomeric DNA, often using a preferred position within the telomerase-bound RNA. Loss of function mutants have reduced telomere length in roots and over a period of generations, decreasing root meristem function. |
TAIR Short Description | telomerase reverse transcriptase |
TAIR Aliases | ATTERT, TERT |