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GO Term : GO:0060070 canonical Wnt signaling pathway GO

Namespace  biological_process Obsolete  false
Description  A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.

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1 Ontology

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13 Parents

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28 Relations

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6 Synonyms

Trail: GOTerm