| Description | The glycosyltransferase 83 family is involved in the modification of lipid A, a component of the lipopolysaccharide (LPS) in bacterial outer membranes. Members of the family catalyze the transfer of specific sugar moieties to lipid A, which is crucial for bacterial resistance to polymyxin and cationic antimicrobial peptides. For example, they transfer the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. This modification helps bacteria evade the host's immune defenses, contributing to their survival and virulence. Some members are also involved in the modification of the LPS inner core by transferring galacturonic acid residues to specific positions, which is essential for the proper assembly and function of the LPS molecule. | Name | Lipid A-modifying glycosyltransferase 83 |
| Short Name | LipidA_mod_glycosyltrf_83 | Type | Family |
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