| Description | This entry includes superkiller protein 3 (Ski3) from yeasts and plants and tetratricopeptide repeat protein 37 (TTC37/SKI3) from animals. They are a component of the Ski complex required for exosome-mediated RNA surveillance [ , , ].In budding yeasts, the SKI complex (Ski2-Ski3-Ski8) is a helicase complex functioning with the RNA-degrading exosome to mediate the 3'-5' messenger RNA (mRNA) decay in turnover and quality-control pathways [ ]. Ski3 has also been shown to repress dsRNA virus propagation by specifically blocking translation of viral mRNAs []. | Name | Ski3/TTC37 |
| Short Name | Ski3/TTC37 | Type | Family |
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