| Description | Protein Z-dependent protease inhibitor (ZPI; MEROPS identifier I04.005) is a member of the serpin superfamily of proteinase inhibitors, corresponding to clade A10 [ , ]. ZPI inhibits coagulation factor Xa, dependent on protein Z (PZ), a vitamin K-dependent plasma protein []. ZPI also inhibits factor XIa in a process that does not require PZ []. In general, SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms []. | Name | Protein Z-dependent peptidase inhibitor, serpin domain |
| Short Name | PZI_serpin_dom | Type | Domain |
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