Description | This entry includes Rho guanine nucleotide exchange factors 10 and 17.ARHGEF10 is a Rho guanine nucleotide exchange factor that may play a role in developmental myelination of peripheral nerves [ ]. It was found to regulate mitotic spindle formation and play a role in the regulation of the cell division cycle [].ARHGEF17 is a guanine nucleotide exchange for for RhoA GTPases; it contains a Dbl homology (DH) domain but lacks the typical pleckstrin homology domain [ ]. | Name | Rho guanine nucleotide exchange factor 10/17 |
Short Name | ARHGEF10/ARHGEF17 | Type | Family |