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Protein Domain : IPR006899

Description  This domain consists of the N terminus of homeobox-containing transcription factor HNF-1. This region contains a dimerisation sequence [ ] and an acidic region that may be involved in transcription activation. Mutations and the common Ala/Val 98 polymorphism in HNF-1 cause the type 3 form of maturity-onset diabetes of the young (MODY3) []. Name  Hepatocyte nuclear factor 1, N-terminal
Short Name  HNF-1_N Type  Domain
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2 Publications

Genomics

1 Cross References

 

Other

0 Child Features

1 Data Sets

0 Parent Features

0 Protein Domain Regions