Description | This is a predicted pore-forming effector domain directly fused to predicted SAVED sensor domain. Binding of a ligand via the SAVED sensor is predicted to activate the Saf-2TM and initiate a cell suicide response. It is a component of a class of conflict systems reliant on the production of second messenger nucleotide or nucleotide derivative [ ]. | Name | SAVED-fused 2TM effector domain |
Short Name | Saf_2TM | Type | Domain |