Description | This entry represents a group of proteins predominantly found in mammals, including human Negative regulator of P-body association, also called P-body dissociating protein or protein NoBody (non-annotated P-body dissociating polypeptide), a microprotein that interacts with mRNA decapping proteins, which remove the 5' cap from mRNAs to promote 5'-to-3' decay. It localises to P-bodies, which are mRNA-decay-associated RNA-protein granules. NoBody promotes dispersal of P-body components and is likely to play a role in the mRNA decapping process. Decapping proteins participate in mRNA turnover and nonsense-mediated decay (NMD) [ ]. | Name | Negative regulator of P-body association |
Short Name | NoBody | Type | Family |