| Description | Alcohol dehydrogenase ( ) (ADH) catalyses the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD. Currently three, structurally and catalytically, different types of alcohol dehydrogenases are known:Zinc-containing 'long-chain' alcohol dehydrogenases.Insect-type, or 'short-chain' alcohol dehydrogenases.Iron-containing alcohol dehydrogenases.Iron-containing ADH's have been found in yeast (gene ADH4) [ ], as well as in Zymomonas mobilis (gene adhB) []. These two iron-containing ADH's are closely related to the following enzymes:Escherichia coli lactaldehyde reductase (also known as propanediol oxidoreductase) ( ) (gene fucO) [ ], an enzyme involved in the metabolism of fucose and which also seems to contain ferrous ion(s).Clostridium acetobutylicum NADPH- and NADH-dependent butanol dehydrogenases ( ) (genes adh1, bdhA and bdhB) [ ], an enzyme which has activity using butanol and ethanol as substrates.E. coli aldehyde-alcohol dehydrogenase (AdhE) [ ], an iron-dependent enzyme which harbor three different activities: alcohol dehydrogenase, acetaldehyde dehydrogenase (acetylating) () and pyruvate-formate-lyase deactivase. Bacterial glycerol dehydrogenase ( ) (gene gldA or dhaD) [ ].Clostridium kluyveri NAD-dependent 4-hydroxybutyrate dehydrogenase (4hbd) ( ). Citrobacter freundii and Klebsiella pneumoniae 1,3-propanediol dehydrogenase ( ) (gene dhaT). Bacillus methanolicus NAD-dependent methanol dehydrogenase ( ) [ ].E. coli and Salmonella typhimurium ethanolamine utilization protein eutG.E. coli hypothetical protein yiaY. | Name | Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA |
| Short Name | ADH_Fe/GldA | Type | Domain |
Powered by
Have you tried our InterMine mobile apps?
and interoperation is funded by 
