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Gene : SCAR2 A. thaliana

DB identifier  ? AT2G38440 Secondary Identifier  ? locus:2057155
Name  ? SCAR homolog 2 Brief Description  SCAR homolog 2
TAIR Computational Description  SCAR homolog 2;(source:Araport11)
TAIR Curator Summary  Encodes a subunit of the WAVE complex. The WAVE complex is required for activation of ARP2/3 complex which functions in actin microfilament nucleation and branching. Mutations cause defects in both the actin and microtubule cytoskeletons that result in aberrant epidermal cell expansion. itb1 mutants showed irregularities in trichome branch positioning and expansion. The SHD domain of this protein binds to BRK1 and overexpression of the SHD domain results in a dominant negative phenotype. The mRNA is cell-to-cell mobile.
TAIR Short Description  SCAR homolog 2
TAIR Aliases  ATSCAR2, DIS3, ITB1, SCAR2, WAVE4

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