| Description | The plant Nitrate transporter/Peptide transporter (NRT1/PTR) family (NPF) is related to the POT (proton-coupled oligopeptide transporter), Peptide transporter (PepT/PTR), or Solute Carrier 15 (SLC15) family in animals [ , ]. In contrast to related animal and bacterial counterparts, the plant proteins transport a wide variety of substrates including nitrate, peptides, amino acids, dicarboxylates, glucosinolates, as well as the plant hormones indole-3-acetic acid (IAA) and abscisic acid (ABA). A study identified eight subfamilies within this family, named NPF1-NPF8 [].This entry represents NPF5, which includes Arabidopsis thaliana PTR3 (AtPTR3, now named AtNPF5.2), a wound-induced peptide transporter that is necessary for defense against virulent bacterial pathogens [ , ]. NPF5 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement []. | Name | NRT1/PTR family |
| Short Name | NRT1/PTR | Type | Family |
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