| Description | The GLEYA domain is related to lectin-like binding domains found in the Saccharomyces cerevisiae Flo proteins and the Candida glabrata Epa proteins [ ]. It is a carbohydrate-binding domain that is found in fungal adhesins (also referred to as agglutinins or flocculins) []. Adhesins with a GLEYA domain possess a typical N-terminal signal peptide and a domain of conserved sequence repeats, but lack glycosylphosphatidylinositol (GPI) anchor attachment signals []. They contain a conserved motif G(M/L)(E/A/N/Q)YA, hence the name GLEYA. Based on sequence homology, it is suggested that the GLEYA domain would predominantly contain β sheets []. The GLEYA domain is also found in Schizosaccharomyces pombe protein , thought to be a kinetochore protein (Sim4 complex subunit), however no direct evidence for kinetochore association has been found [ ]. Furthermore, a global protein localisation study in S. pombe identified it as a secreted protein localized to the Golgi complex []. | Name | GLEYA adhesin domain |
| Short Name | GLEYA_adhesin_domain | Type | Domain |
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