| Description | This entry represents the catalytic (Rossmann-fold) domain found in cysteinyl tRNA synthetases [ ] which is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.Cysteine-tRNA ligase (also known as cysteinyl-tRNA synthetase) ( ) is an alpha monomer and belongs to class Ia [ ]. It aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. It is highly specific despite not possessing the amino acid editing activity characteristic of many other tRNA ligases [, , , , , , , , , , , ]. | Name | tRNA synthetases class I, catalytic domain |
| Short Name | tRNA-synt_1_cat_dom | Type | Domain |
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