Description | 3-Hydroxyisobutyrate is a central metabolite in the valine catabolic pathway, and is reversibly oxidised to methylmalonate semi-aldehyde by a specific dehydrogenase belonging to the 3-hydroxyacid dehydrogenase family. This entry represents the NAD-binding domain of 3-hydroxyisobutyrate dehydrogenase related sequences, such as 6-phosphogluconate dehydrogenase, that adopts a Rossmann fold [ ]. | Name | 3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain |
Short Name | HIBADH-like_NADP-bd | Type | Domain |