| Description | This domain is found in the toxin ExoU from Pseudomonas aeruginosa ( ) and similar sequences mainly found in Gammaproteobacteria. ExoU, an effector of the type III secretion system of the bacteria, is a patatin-like phospholipase that binds to the host membranes and induces cytotoxic effects leading to rapid necrotic cell death. This protein shows four domains: a putative chaperone binding domain. a patatin-like domain ( ), and two domains that form the membrane localization domain (MLD). This entry represents the C-terminal domain, which folds into a four-helical bundle with a conserved arginine exposed. This residue seems to be essential for localisation [ , , ]. | Name | ExoU toxin, C-terminal domain |
| Short Name | ExoU_C | Type | Domain |
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