Description | This entry represents a galactose-binding domain-like found in Hemicentin and Willebrand factor A domain-containing protein 7 (VWA7).HMCN1 is involved in transforming growth factor beta-mediated rearrangement of the podocyte cytoskeleton which includes reduction of F-actin fibres and broadening, flattening and elongation of podocytes [ ]. HMCN1 is also implicated in the organisation of the basement membrane [] and may contribute to cleavage furrow maturation during cytokinesis in embryos [].VWA7 is found in the major histocompatibility complex class III region and it is likely implicated in lung cancers [ ] | Name | Hemicentin/VWA7, galactose-binding domain-like |
Short Name | GBD_Hemicentin/VWA7 | Type | Domain |