| Description | Cannabinoid receptors are a class of cell membrane receptors that belong to the rhodopsin-like G-protein coupled receptor (GPCR) family [ , , ]. Typical of G protein-coupled receptors, cannabinoid receptors contain seven transmembrane spanning domains []. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, such as N-arachidonoylethanolamine and 2-arachidonoyl glycerol (produced by the mammalian body), plant cannabinoids, such as tetrahydrocannabinol [, ] (produced by the plantCannabis sativa) and synthetic cannabinoids, such as HU-210 [ ]. Currently, two known cannabinoid receptor subtypes have been identified, CB1 receptor and CB2 receptor [, ], and are phylogenetically restricted to the chordate branch of the animal kingdom []. The International Union of Basic and Clinical Pharmacology (IUPHAR) has identified five pharmacological targets that could be used to find new cannabinoid receptors or channels [], which has resulted in a number of cannabinoid receptors being considered. TRP vanilloid 1, which is thought to function as an ionotropic cannabinoid receptor [], and some deorphanised GPCRs []: GPR18, GPR55, GPR119. However, according to the criteria, no channel, non-CB1/CB2 established receptor or deorphanised receptor can currently be classified fully as a novel cannabinoid receptor [].This entry represents the cannabinoid receptor family, which includes cannabinoid receptor 1 and cannabinoid receptor 2. | Name | Cannabinoid receptor family |
| Short Name | Cnbnoid_rcpt | Type | Family |
Powered by
Have you tried our InterMine mobile apps?
and interoperation is funded by 
