Description | This entry represents the C-terminal domain of the siroheme biosynthesis protein Met8. In Saccharomyces cerevisiae, Met8 is a bifunctional dehydrogenase ( ) and ferrochelatase ( ) [ ]. It catalyses the final two steps in the biosynthesis of sirohaem, involving a NAD(+)-dependent dehydrogenation of precorrin-2 to generate sirohydrochlorin followed by ferrochelation to yield sirohaem []. | Name | Siroheme biosynthesis protein Met8, C-terminal |
Short Name | Met8_C | Type | Domain |