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Gene : BASL A. thaliana

DB identifier  ? AT5G60880 Secondary Identifier  ? locus:2159305
Name  ? BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE Brief Description  breaking of asymmetry in the stomatal lineage
TAIR Computational Description  breaking of asymmetry in the stomatal lineage;(source:Araport11)
TAIR Curator Summary  Encodes BASL (BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE), a regulator of asymmetric divisions. In asymmetrically dividing stomatal-lineage cells, BASL accumulates in a polarized crescent at the cell periphery before division, and then localizes differentially to the nucleus and a peripheral crescent in self-renewing cells and their sisters after division. Its transcript levels change after inducing MUTE expression in a mute background.
TAIR Short Description  breaking of asymmetry in the stomatal lineage
TAIR Aliases  BASL

5 Gene Rifs

1 Organism

20 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 1548  
Location: Chr5:24488289-24489836 reverse strand

Gene models - BASL AT5G60880

? Gene models

Transcripts: 2  Exons: 9  Introns: 7 

Overlapping Features

? Genome features that overlap coordinates of this Gene

9 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
BASL_ARATH BASL_ARATH-2 developmental stage First observed in nuclei of epidermal cells 16 hours post germination (PubMed:19523675). Later confined to cells undergoing asymmetric divisions (e.g. stomatal lineage cells) (PubMed:19523675). Expressed in protodermal cells in young seedlings (PubMed:30429609). Copolarizes with YDA and MPK3/MPK6 in stomatal asymmetric cell division (ACD) cells (PubMed:27746029).
BASL_ARATH BASL_ARATH-2 function Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH (PubMed:25843888, PubMed:30429609). Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus (PubMed:25843888, PubMed:30429609). When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD (PubMed:25843888). Cortical polarization leads to elevated nuclear MPK6 signaling and lowered SPCH abundance in one of the two daughter cells, thus differentiating the two daughter cells after ACD (PubMed:27746029).
BASL_ARATH BASL_ARATH-2 subcellular location Dynamic and highly polarized subcellular localization at the cortical polarity in a phosphorylation status-dependent manner (PubMed:19523675, PubMed:21903812, PubMed:25843888, PubMed:27422992, PubMed:27746029, PubMed:30429609). Polarity is only exhibited by one daughter cell after an asymmetric cell division (PubMed:27746029). ASK7/BIN2-mediated nuclear exclusion (PubMed:30429609). First localized to the nucleus in asymmetric cell division (ACD) precursors (PubMed:30429609). In asymmetrically dividing stomatal-lineage cells, before division, accumulates in a polarized crescent at the cell periphery (e.g. meristemoid mother cells (MMCs)), and, after division, localizes differentially to the nucleus (e.g. in meristemoids) and a peripheral crescent in self-renewing cells and their sisters (e.g. stomatal lineage ground cell (SLGC)) (PubMed:19523675, PubMed:25843888, PubMed:27422992, PubMed:30429609). Localized in the cell periphery at a position that minimizes the inverse distance from all points along the new division boundaries (PubMed:21903812).
BASL_ARATH BASL_ARATH-2 tissue specificity Mostly expressed in stomatal lineage cells including asymmetrically dividing meristemoid mother cells (MMCs) and meristemoids, and, at lower levels, in their sisters (PubMed:19523675, PubMed:27422992). Also present in vasculature (PubMed:19523675). Expressed at low levels in the epidermal pavement cells (PubMed:27422992).

2 Proteins

Function

Gene Ontology

cellular component
nucleus  ? ECO  
cell cortex  ? ECO  
extrinsic component of plasma membrane  ? ECO  
molecular function
No terms in this category.
biological process
unidimensional cell growth  ? ECO  
asymmetric cell division  ? ECO  
regulation of asymmetric cell division  ? ECO  
stomatal complex development  ? ECO  

Interactions

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

8 Data Sets