Genomics
Genome feature
| Region: |
gene
|
Length: |
1548
 |
| Location: | Chr5:24488289-24489836 reverse strand | ||
Overlapping Features
Genome features that overlap coordinates of this Gene
Proteins
Curated comments from UniProt
| Type | Comment | Proteins |
|---|---|---|
| BASL_ARATH BASL_ARATH-2 | developmental stage | First observed in nuclei of epidermal cells 16 hours post germination (PubMed:19523675). Later confined to cells undergoing asymmetric divisions (e.g. stomatal lineage cells) (PubMed:19523675). Expressed in protodermal cells in young seedlings (PubMed:30429609). Copolarizes with YDA and MPK3/MPK6 in stomatal asymmetric cell division (ACD) cells (PubMed:27746029). |
| BASL_ARATH BASL_ARATH-2 | function | Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH (PubMed:25843888, PubMed:30429609). Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus (PubMed:25843888, PubMed:30429609). When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD (PubMed:25843888). Cortical polarization leads to elevated nuclear MPK6 signaling and lowered SPCH abundance in one of the two daughter cells, thus differentiating the two daughter cells after ACD (PubMed:27746029). |
| BASL_ARATH BASL_ARATH-2 | subcellular location | Dynamic and highly polarized subcellular localization at the cortical polarity in a phosphorylation status-dependent manner (PubMed:19523675, PubMed:21903812, PubMed:25843888, PubMed:27422992, PubMed:27746029, PubMed:30429609). Polarity is only exhibited by one daughter cell after an asymmetric cell division (PubMed:27746029). ASK7/BIN2-mediated nuclear exclusion (PubMed:30429609). First localized to the nucleus in asymmetric cell division (ACD) precursors (PubMed:30429609). In asymmetrically dividing stomatal-lineage cells, before division, accumulates in a polarized crescent at the cell periphery (e.g. meristemoid mother cells (MMCs)), and, after division, localizes differentially to the nucleus (e.g. in meristemoids) and a peripheral crescent in self-renewing cells and their sisters (e.g. stomatal lineage ground cell (SLGC)) (PubMed:19523675, PubMed:25843888, PubMed:27422992, PubMed:30429609). Localized in the cell periphery at a position that minimizes the inverse distance from all points along the new division boundaries (PubMed:21903812). |
| BASL_ARATH BASL_ARATH-2 | tissue specificity | Mostly expressed in stomatal lineage cells including asymmetrically dividing meristemoid mother cells (MMCs) and meristemoids, and, at lower levels, in their sisters (PubMed:19523675, PubMed:27422992). Also present in vasculature (PubMed:19523675). Expressed at low levels in the epidermal pavement cells (PubMed:27422992). |
Function
Gene Ontology
| cellular component | |
|---|---|
|
nucleus
|
ECO |
|
cell cortex
|
ECO |
|
extrinsic component of plasma membrane
|
ECO |
| molecular function | |
| No terms in this category. | |
| biological process | |
|
unidimensional cell growth
|
ECO |
|
asymmetric cell division
|
ECO |
|
regulation of asymmetric cell division
|
ECO |
|
stomatal complex development
|
ECO |
Interactions
Interaction Network
Show the following interaction types:
Reset view
Show in table format
Export graph
- Click on a gene to get more info about it.
BAR Webservices
