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Gene : NPR3 A. thaliana

DB identifier  ? AT5G45110 Secondary Identifier  ? locus:2153192
Name  ? NPR1-like protein 3 Brief Description  NPR1-like protein 3
TAIR Computational Description  NPR1-like protein 3;(source:Araport11)
TAIR Curator Summary  Encodes NPR3, a paralog of NPR1. Involved in negative regulation of defense responses against bacterial and oomycete pathogens. npr3 mutants has elevated level of PR1 expression. Interacts with TGA2, TGA3, TGA5 and TGA6 in yeast two hybrid assays. NPR3 and NPR4 are receptors for the immune signal salicylic acid. The mRNA is cell-to-cell mobile.
TAIR Short Description  NPR1-like protein 3
TAIR Aliases  ATNPR3, NPR3

5 Gene Rifs

1 Organism

32 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 2821  
Location: Chr5:18228768-18231588

Gene models - NPR3 AT5G45110

? Gene models

Transcripts: 2  Exons: 7  Introns: 5 

Overlapping Features

? Genome features that overlap coordinates of this Gene

8 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
NPR3_ARATH function Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of NPR1 in response to SA (PubMed:22699612, PubMed:32788727). Together with NPR4, acts as receptor of salicylic acid to monitor immunity in a NPR1-dependent manner and induce systemic acquired resistance (SAR) (PubMed:22699612, PubMed:32788727). Involved in the regulation of basal defense responses against pathogens, and may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways (PubMed:17076807).
NPR3_ARATH A0A1P8BAP1_ARATH pathway Protein modification; protein ubiquitination.
NPR3_ARATH A0A1P8BAP1_ARATH similarity Belongs to the plant 'ANKYRIN-BTB/POZ' family. 'NPR1-like' subfamily.

2 Proteins

Function

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets