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Gene : MIS12 A. thaliana

DB identifier  ? AT5G35520 Secondary Identifier  ? locus:2169508
Name  ? MINICHROMOSOME INSTABILITY 12 (MIS12)-LIKE Brief Description  minichromosome instability 12 (mis12)-like protein
TAIR Computational Description  minichromosome instability 12 (mis12)-like protein;(source:Araport11)
TAIR Curator Summary  encodes a homologue of the yeast (S. pombe) Mis12 (minichromosome instability) protein. MIS12 co-localizes with 180 bp repeats of centromeric DNA throughout the cell cycle with a similar pattern to AtCENH3/HTR12. Neither of these two proteins completely cover the 180 bp regions based on FISH analysis.
TAIR Short Description  minichromosome instability 12 (mis12)-like
TAIR Aliases  ATMIS12, MIS12

0 Gene Rifs

1 Organism

5 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 1952  
Location: Chr5:13701290-13703241

Gene models - MIS12 AT5G35520

? Gene models

Transcripts: 1  Exons: 7  Introns: 6 

Overlapping Features

? Genome features that overlap coordinates of this Gene

8 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
MIS12_ARATH function Constitutive component of kinetochores that is essential for proper cell division during mitotic cell cycle (Probable). May play a role in the modulation of centromere during meiosis (PubMed:21695238).
MIS12_ARATH similarity Belongs to the mis12 family.
MIS12_ARATH subcellular location Localizes at centromeric regions throughout the mitotic cell cycle. Co-localizes with CENH3 during the cell cycle, from interphase to anaphase (PubMed:16331414). Localized at centromeres in meiotic cells (PubMed:21695238).

1 Proteins

Function

Gene Ontology

cellular component
MIS12/MIND type complex  ? ECO  
nucleus  ? ECO  
chromosome, centromeric region  ? ECO  
molecular function
No terms in this category.
biological process
mitotic cell cycle  ? ECO  
meiotic cell cycle  ? ECO  
cell division  ? ECO  

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

6 Data Sets