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Gene : BIN4 A. thaliana

DB identifier  ? AT5G24630 Secondary Identifier  ? locus:2153939
Name  ? brassinosteroid-insensitive4 Brief Description  double-stranded DNA binding protein
TAIR Computational Description  double-stranded DNA binding protein;(source:Araport11)
TAIR Curator Summary  This gene is predicted to encode a protein that forms part of the topoisomerase VI complex. BIN4 is a nuclear-localized protein that can bind DNA. bin4 mutants are brassinolide-insensitive dwarves with severely reduced cell size in leaves, roots, and hypocotyls. Proper development of root hairs and trichomes is also disrupted in bin4 mutants and they have elevated levels of double strand breaks in their cotyledon cells.
TAIR Short Description  double-stranded DNA binding
TAIR Aliases  BIN4, MID

2 Gene Rifs

1 Organism

9 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3810  
Location: Chr5:8432384-8436193 reverse strand

Gene models - BIN4 AT5G24630

? Gene models

Transcripts: 12  Exons: 163  Introns: 151 

Overlapping Features

? Genome features that overlap coordinates of this Gene

38 Child Features

1 Cross References

0 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
BIN4_ARATH developmental stage Ubiquitously expressed at low levels during the mitotic cell cycle.
BIN4_ARATH function Component of the DNA topoisomerase VI complex. Binds to DNA. Required for chromatin organization and progression of endoreduplication cycles. The loss of BIN4 activates the ATM- and ATR-dependent DNA damage responses in postmitotic cells and induces the ectopic expression of the mitotic G2/M-specific cyclin B1;1 gene in non-dividing cells.
BIN4_ARATH tissue specificity Expressed in expanding cotyledons, vascular cells, elongating root cells, developing leaf trichomes, root and apical meristems and lateral root primordia.

8 Proteins

Function

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

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Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets