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Gene : CNGC18 A. thaliana

DB identifier  ? AT5G14870 Secondary Identifier  ? locus:2185510
Name  ? cyclic nucleotide-gated channel 18 Brief Description  cyclic nucleotide-gated channel 18
TAIR Computational Description  cyclic nucleotide-gated channel 18;(source:Araport11)
TAIR Curator Summary  Encodes a member of the cyclic nucleotide gated channel family that is asymmetrically localized to the plasma membrane at the growing tip of the pollen tube and is involved in pollen tube growth and pollen tube guidance to ovules. It likely directly transduces a cNMP signal into an ion flux that can produce a localized signal capable of regulating the pollen tip-growth machinery. Also functions as a Ca2+ permeable channel.
TAIR Short Description  cyclic nucleotide-gated channel 18
TAIR Aliases  ATCNGC18, CNGC18

5 Gene Rifs

1 Organism

15 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3003  
Location: Chr5:4808091-4811093 reverse strand

Gene models - CNGC18 AT5G14870

? Gene models

Transcripts: 1  Exons: 6  Introns: 5 

Overlapping Features

? Genome features that overlap coordinates of this Gene

7 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
CNG18_ARATH function Cyclic nucleotide-gated ion channel required for directional pollen tube growth into the transmitting tract (PubMed:17726111, PubMed:26929345). Acts as a Ca(2+)-permeable divalent cation-selective channel inhibited by either lanthanum or gadolinium (PubMed:24380879). Regulated by CPK32 to mediate Ca(2+) transport across the plasma membrane in response to Ca(2+) oscillation (PubMed:24121288).
CNG18_ARATH similarity Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
CNG18_ARATH subcellular location focused at the cell perimeter of the growing pollen tube tip.
CNG18_ARATH tissue specificity Expressed in pollen grains. Not detected in leaves, roots or root hairs.

1 Proteins

Function

Gene Ontology

cellular component
cytoplasmic vesicle membrane  ? ECO  
apical plasma membrane  ? ECO  
molecular function
calmodulin binding  ? ECO  
cAMP binding  ? ECO  
calcium channel activity  ? ECO  
cGMP binding  ? ECO  
biological process
intracellular calcium ion homeostasis  ? ECO  
pollen tube growth  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets