DB identifier
|
AT5G13570 | Secondary Identifier
|
locus:2173174 |
| Name
|
decapping 2 | Brief Description | decapping 2 |
| TAIR Computational Description | decapping 2;(source:Araport11) |
| TAIR Curator Summary | Encodes DCP2 with mRNA decapping activity. DCP2 forms a mRNA decapping complex with DCP1 (At1g08370) and VCS (VARICOSE) (At3g13300). Recombinant DCP2 is enzymatically active in vitro, generating from capped mRNAs m7GDP, and 5’-phosphorylated mRNAs. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. The protein was shown by immunoprecipitation not to interact with DCP1. |
| TAIR Short Description | decapping 2 |
| TAIR Aliases | ATDCP2, DCP2, ITS1, TDT |
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