Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
CRN_ARATH-2 CRN_ARATH-3 CRN_ARATH | developmental stage | First observed in 16-cells stage embryo and surrounding region. From early heart to early torpedo stage, confined to the developing vasculature of the hypocotyl, cotyledons, and developing root. Faint expression in the emerging shoot apical meristem (SAM) at the torpedo stage. After germination, present in root, shoot and inflorescence meristems, as well as in young flower primordia and ovules (PubMed:18381924). In roots, detected in the stele, endodermis basal and cortex cells, and at the end of the root meristem, comprising the quiescent center, surrounding initials, and vascular precursors (PubMed:18381924, PubMed:27229734). Also present in the vasculature of primary and lateral roots, in the pericycle at sites of lateral root initiation, in lateral root meristems, and in the vasculature of the leaves. Accumulates in stamen and carpel primordia. Expressed in young provascular tissue of floral organs and stem tissue (PubMed:18381924). |
CRN_ARATH-2 CRN_ARATH-3 CRN_ARATH | function | Involved in the perception of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristem maintenance. Modulates root, shoot and flower apical meristem maintenance and floral organ development regulation, probably via CLAVATA (CLV)-like pathways involving at least CLV3 and CLE19. In complex with CLV2, perceives secreted CLV3-like effector proteins from plant-parasitic cyst nematodes as ligand mimics of the plant CLE signaling pathway (PubMed:21265896). This recognition is required for proper feeding structure (syncytium) development and ultimately successful nematode infection (PubMed:21265896). CLE14 perception by CLV2/CRN complex triggers root meristem differentiation (PubMed:20697738, PubMed:28586647). Required for the sensing of the root CLE peptides (e.g. CLE8, CLE9/CLE10, CLE11, CLE13, CLE14, CLE16, CLE17, CLE18, CLE20, CLE21, CLE25, CLE26, CLE40, CLE41/CLE44 and CLE45), which also involves CLV2 and leads to root growth regulation, mostly in the phloem and protophloem (PubMed:28607033). Promotes the accumulation of BAM3, especially at later stages of protophloem development (PubMed:28607033). |
CRN_ARATH-2 CRN_ARATH-3 CRN_ARATH | similarity | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. |
CRN_ARATH-2 CRN_ARATH-3 CRN_ARATH | subcellular location | Requires CLV2 for export from the endoplasmic reticulum and localization to the plasma membrane. |
CRN_ARATH-2 CRN_ARATH-3 CRN_ARATH | tissue specificity | Present in roots, stems, leaves, inflorescence, flowers and siliques. Mostly expressed in shoot tips and, to a lesser extent, in young organs and roots. Also expressed in the inner tissues of the proximal root meristem (PubMed:21265896). Expressed in the vascular cylinder of root tips, mostly in phloem poles (PubMed:28607033). |
Function
Gene Ontology
cellular component | |
---|---|
endoplasmic reticulum membrane | ECO |
plasma membrane | ECO |
molecular function | |
ATP binding | ECO |
peptide receptor activity | ECO |
receptor serine/threonine kinase binding | ECO |
signaling receptor binding | ECO |
biological process | |
protein phosphorylation | ECO |
regulation of cell differentiation | ECO |
regulation of meristem growth | ECO |
maintenance of root meristem identity | ECO |
regulation of flower development | ECO |
phloem development | ECO |
Interactions
Interaction Network
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