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Gene : CLE40 A. thaliana

DB identifier  ? AT5G12990 Secondary Identifier  ? locus:2182325
Name  ? CLAVATA3/ESR-RELATED 40 Brief Description  CLAVATA3/ESR-RELATED 40
TAIR Computational Description  CLAVATA3/ESR-RELATED 40;(source:Araport11)
TAIR Curator Summary  Member of a large family of putative ligands homologous to the Clavata3 gene. Consists of a single exon.
TAIR Short Description  CLAVATA3/ESR-RELATED 40
TAIR Aliases  CLE40

4 Gene Rifs

1 Organism

23 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 551  
Location: Chr5:4109234-4109784 reverse strand

Gene models - CLE40 AT5G12990

? Gene models

Transcripts: 1  Exons: 3  Introns: 2 

Overlapping Features

? Genome features that overlap coordinates of this Gene

CDSs: 3, Exons: 3, Five Prime UTR: 1, mRNA: 1

4 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
CLE40_ARATH developmental stage Expressed in the entire embryo at the globular stage. Progressively restricted to the basal regions of the embryo that form the root meristem and the vasculature. After germination, detected in the differentiation zone of the stele that forms the inner layers of the root and in differentiating columella cells (CCs).
CLE40_ARATH function Extracellular signal peptide secreted by differentiated root cells that regulates root cell fate. Acts with ACR4 as a ligand-receptor pair in a signal transduction pathway, coordinating movement of the root tip and organization of cell divisions in the root meristem. Promotes cell differentiation in the distal root meristem in a dose-dependent manner, especially the transition from columella stem cells (CSC) daughters into columella cells (CCs). Induces ACR4 expression in root quiescent center (QC). Involved in WUX5 QC-specific expression pattern regulation. Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2 (PubMed:28607033).
CLE40_ARATH similarity Belongs to the CLV3/ESR signal peptide family.
CLE40_ARATH tissue specificity Mostly expressed at low levels in stems and apex, and, to a lower extent, in roots, seedlings, leaves, flowers, siliques and pollen.

1 Proteins

Function

Gene Ontology

cellular component
apoplast  ? ECO  
molecular function
receptor serine/threonine kinase binding  ? ECO  
biological process
regulation of cell differentiation  ? ECO  
cell fate specification  ? ECO  
maintenance of root meristem identity  ? ECO  
cell-cell signaling involved in cell fate commitment  ? ECO  
phloem development  ? ECO  

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

7 Data Sets