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Gene : AT5G11470 A. thaliana

DB identifier  ? AT5G11470 Secondary Identifier  ? locus:2144256
Brief Description  bromo-adjacent homology (BAH) domain-containing protein
TAIR Computational Description  bromo-adjacent homology (BAH) domain-containing protein;(source:Araport11)
TAIR Curator Summary  SG1 is a Bromo-Adjacent Homology (BAH) domain containing protein involved in CHG methylation within genebodies. Loss of function results in pleiotrophic developmental effects that increase after 4 generations.
TAIR Short Description  bromo-adjacent homology (BAH) domain-containing protein
TAIR Aliases  ASI1, IBM2, SG1

6 Gene Rifs

1 Organism

10 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 5581  
Location: Chr5:3662634-3668214 reverse strand

Gene models - AT5G11470 AT5G11470

? Gene models

Transcripts: 2  Exons: 26  Introns: 24 

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19 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
ASI1_ARATH function Collaboratively with AIPP1/EDM3 and EDM2, the AAE complex regulates alternative RNA processing (e.g. alternative splicing) and epigenetic silencing (e.g. H3K9me2) of intronic heterochromatin-containing genes as well as genic heterochromatin-containing genes by promoting distal 3' polyadenylation; may associate with intronic heterochromatin and bind gene transcripts to modulate polyadenylation (PubMed:24003136, PubMed:28808009, PubMed:33438356). Required to prevent promoter DNA hypermethylation and transcriptional silencing of some transgenes (PubMed:24003136). Plays a similar role to that of the histone H3K9 demethylase JMJ25/IBM1 in preventing CHG methylation in the bodies of numerous genes. RNA-binding protein that ensures the proper expression of JMJ25/IBM1 full-length transcript by associating with an intronic heterochromatic repeat element of JMJ25/IBM1 (PubMed:23934508, PubMed:24003136, PubMed:24404182). Modulates also transposable elements (TE) expression (PubMed:28808009, PubMed:33438356). Contributes to a unique mechanism to deal with the collateral effect of silencing intronic repeat elements (PubMed:23934508, PubMed:24003136, PubMed:24404182).

1 Proteins

Function

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Interactions

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Expression

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Homology

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0 Homologues

 

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7 Data Sets