Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
IF2A_ARATH | function | Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF2B. |
IF2A_ARATH | similarity | Belongs to the eIF-2-alpha family. |
Function
Gene Ontology
cellular component | |
---|---|
eukaryotic translation initiation factor 2 complex | ECO |
cytosol | ECO |
plasma membrane | ECO |
molecular function | |
translation initiation factor activity | ECO |
RNA binding | ECO |
biological process | |
No terms in this category. |
Interactions
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