Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
MORC2_ARATH | function | Mediator of defense signaling triggered by distinct classes of R proteins. Required during hypersensitive response (HR) that confers disease resistance to turnip crinkle virus (TCV) (PubMed:19704828). Contributes to resistance against Pseudomonas syringae and Hyaloperonospora arabidopsidis, at early stages prior to cytosolic calcium ions Ca(2+) accumulation (PubMed:20332379). Required for pathogen-associated molecular pattern (PAMP)-triggered immunity, basal resistance, non-host resistance and systemic acquired resistance (SAR) (PubMed:23250427). Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. May also be involved in the regulation of chromatin architecture to maintain gene silencing (PubMed:24799676). Exhibits ATPase activity (By similarity). |
MORC2_ARATH | similarity | Belongs to the MORC ATPase protein family. |
MORC2_ARATH | subcellular location | Present in nuclear bodies near chromocenters. Localized in endosome-like vesicles displaying rapid cytosolic streaming. Accumulates in the nucleus following pathogen-associated molecular pattern (PAMP) treatment or infection with an avirulent pathogen. |
Function
Gene Ontology
cellular component | |
---|---|
endosome | ECO |
nucleus | ECO |
molecular function | |
ATP binding | ECO |
ATP hydrolysis activity | ECO |
endonuclease activity | ECO |
DNA binding | ECO |
kinase activity | ECO |
RNA binding | ECO |
biological process | |
defense response to virus | ECO |
regulation of DNA repair | ECO |
plant-type hypersensitive response | ECO |
DNA repair | ECO |
positive regulation of systemic acquired resistance | ECO |
positive regulation of defense response to bacterium | ECO |
phosphorylation | ECO |
regulatory ncRNA-mediated gene silencing | ECO |
chromatin organization | ECO |