help  | faq  | software  | BAR
Hide

Oops!

https://bar.utoronto.ca/thalemine/service/ is incorrect
Hide

Oops!

Error: 403

Gene : MLH3 A. thaliana

DB identifier  ? AT4G35520 Secondary Identifier  ? locus:2127923
Name  ? MUTL protein homolog 3 Brief Description  MUTL protein homolog 3
TAIR Computational Description  MUTL protein homolog 3;(source:Araport11)
TAIR Curator Summary  DNA mismatch repair protein similar to MutL. Required for normal levels of meiotic crossovers
TAIR Short Description  MUTL protein homolog 3
TAIR Aliases  ATMLH3, MLH3

0 Gene Rifs

1 Organism

7 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 6224  
Location: Chr4:16865304-16871527

Gene models - MLH3 AT4G35520

? Gene models

Transcripts: 8  Exons: 167  Introns: 159 

Overlapping Features

? Genome features that overlap coordinates of this Gene

CDSs: 168, Exons: 34, Five Prime UTRs: 4, Gene: 1, mRNAs: 9

41 Child Features

0 Cross References

1 Downstream Intergenic Region

0 Located Features

0 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
MLH3_ARATH developmental stage Expressed during prophase I of meiosis.
MLH3_ARATH function Involved in DNA mismatch repair (MMR), correcting insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLbeta heterodimer, which probably forms a ternary complex with the MutSbeta heterodimer that initially recognizes the DNA mismatches. This complex is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in promoting meiotic crossing-over and is involved in maintaining the genetic stability of simple sequence repeats by correction of frameshift intermediates.
A0A1P8B434_ARATH A0A1P8B439_ARATH A0A1P8B445_ARATH MLH3_ARATH A0A1P8B465_ARATH A0A1P8B429_ARATH similarity Belongs to the DNA mismatch repair MutL/HexB family.
MLH3_ARATH tissue specificity Expressed in reproductive tissues.

8 Proteins

Function

Gene Ontology

cellular component
mismatch repair complex  ? ECO  
chromosome  ? ECO  
nucleus  ? ECO  
molecular function
ATP binding  ? ECO  
ATP hydrolysis activity  ? ECO  
ATP-dependent DNA damage sensor activity  ? ECO  
biological process
reciprocal meiotic recombination  ? ECO  
mismatch repair  ? ECO  

Interactions

Interaction Network

Show the following interaction types:
Reset view
Show in table format
Export graph

Click on a gene to get more info about it.

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

6 Data Sets