help  | faq  | software  | BAR
Hide Your session has expired. If you were not logged in, your data (including query history and any lists you made) has been cleared.Your session has expired. If you were not logged in, your data (including query history and any lists you made) has been cleared.

Gene : PFN2 A. thaliana

DB identifier  ? AT4G29350 Secondary Identifier  ? locus:2118324
Name  ? profilin 2 Brief Description  profilin 2
TAIR Computational Description  profilin 2;(source:Araport11)
TAIR Curator Summary  Encodes profilin2, a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton. Expressed in vegetative organs. The first intron of PRF2 enhances gene expression. The mRNA is cell-to-cell mobile.
TAIR Short Description  profilin 2
TAIR Aliases  AtPRF2, PFN2, PRF2, PRO2

2 Gene Rifs

1 Organism

32 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 1507  
Location: Chr4:14449888-14451394

Gene models - PFN2 AT4G29350

? Gene models

Transcripts: 1  Exons: 3  Introns: 2 

Overlapping Features

? Genome features that overlap coordinates of this Gene

4 Child Features

1 Cross References

0 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
PRF2_ARATH function Binds to actin monomers and regulates the organization of the actin cytoskeleton (PubMed:21090759). At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (PubMed:16313636, PubMed:26996265, PubMed:29861135). At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate (PubMed:29861135). Binds G-actin and poly-L-proline with low affinity in vitro (PubMed:19200149). Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization (PubMed:26578694). May be involved in the cross-talk between vesicular trafficking and the actin cytoskeleton (PubMed:21090759). At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity). Inhibits cell growth of various pathogenic fungal strains (PubMed:30056100). May play a role as antifungal proteins in the defense system against fungal pathogen attacks (PubMed:30056100).
PRF2_ARATH similarity Belongs to the profilin family.
PRF2_ARATH tissue specificity Expressed in vascular bundles of roots, hypocotyls, cotyledons, leaves, sepals, petals, stamen filaments and stalks of developing seeds (PubMed:16361517, PubMed:8771785). Expressed in leaf epidermal cells, trichomes and stem epidermal cells (PubMed:19200149). Detected in phloem exudates (at protein level) (PubMed:30056100).

1 Proteins

Function

Gene Ontology

cellular component
endoplasmic reticulum  ? ECO  
cytosol  ? ECO  
plasma membrane  ? ECO  
cytoskeleton  ? ECO  
nucleus  ? ECO  
chloroplast  ? ECO  
cytoplasm  ? ECO  
molecular function
actin binding  ? ECO  
biological process
actin polymerization or depolymerization  ? ECO  
defense response  ? ECO  
inflorescence development  ? ECO  
leaf development  ? ECO  
lateral root development  ? ECO  

Interactions

Interaction Network

Show the following interaction types:
Reset view
Show in table format
Export graph

Click on a gene to get more info about it.

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets